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1.
Pakistan Journal of Pharmaceutical Sciences. 2017; 30 (3): 697-703
in English | IMEMR | ID: emr-186463

ABSTRACT

The present paper investigates antioxidant, antimicrobial and photochemical screening different extracts of Fagonia olivieri. Analysis of the data indicated that the subject plant contained a good amount of flavonoids, tannins, saponins, terpenoids and steroids. Maximum concentrations of phenolic compounds was found in methanol fraction [29.0+/-6.12 mg GAE/g] while minimum [22.10+/-6.31mg GAE/g] in methylated spirit fraction. Similarly, ethanol fraction contained higher concentration of flavonoid content [135.4+/-7.63mg Quercetin/g] followed by methanol fraction [138.4+/-2.96 mg Quercetin/g]. Analysis of the data revealed that maximum antioxidant activity was recorded in mthylated spirit fraction [IC[50]= 10.69+/-1.66] followed by methanol fraction [IC[50]= 9.10+/-0.76] while no activity was noted in hexane fraction. The data indicated good antibacterial and antifungal activity against S. typhi, S. aureus, P. aeruginosa and A. flavus

2.
Pakistan Journal of Pharmaceutical Sciences. 2016; 29 (3): 861-868
in English | IMEMR | ID: emr-179555

ABSTRACT

The present study reveals antimicrobial potentials and phytochemical analysis of A. javanica and L. ustitatissimum. Phytochemical analysis indicated that the tested plants contained a substantial amount of flavonoids, terpenoids and steroids while saponins and tannins were absent in L. ustitatissimum, however, tannins were present in A. javanica. L. ustitatissimum contained maximum total phenolic content of 166.36mg/g in methylated spirit fraction while its ethyl acetate fraction contained highest quantity of flavonoids 27.6mg/g in case of Aerva javanica. Antimicrobial potentials of the subject plants revealed that L. ustitatissimum had maximum antibacterial activity [MIC=4.33microg/ml] while A. javanica was most effective against fungal strains [MIC=2.66 microg/ml]

3.
Pakistan Journal of Pharmaceutical Sciences. 2016; 29 (6): 2039-2045
in English | IMEMR | ID: emr-184146

ABSTRACT

The present study investigates the nutritive and anti-nutritive composition of six species [Allium porrum, Amaranthus spinosis, Apium graveolens, Caralluma edulis, Chenopodium album, Urtica dioica]. The studied species contained considerable amount of crude protein [4.53-11.41%], crude fat [1.25-3.74%], vitamin C [7.85-28.09mg 100[-1]g] and beta-Carotene [18.29-169.33mg 100]-1]g]. The mineral profile of Chenopodium album is considered as potential source of Zn [14.51 +/- 1.14mg 100[-1]g], Mn [67.71 +/- 0.85mg 100[-1]g], Se [8.45 +/- 0.49mg 100[-1]g] and Fe [182.08 +/- 1.52mg 100[-1]g] and Caralluma edulis as potential source of Fe [7.28 +/- 0.03mg 100[-1]g]. Ca and P content ranged 63-306mg 100[-1] g and 12-392mg 100[-1] g in all studied plants with exceptionally high level was found in Chenopodium album [1084mg 100[-1]g] and [3924mg 100[-1]g], respectively. Similarly, total phenol, tannin and phytic acid were found in the range of 105-354, 5-90 and 10-85mg 100[-1]g, respectively. Total oxalates and soluble oxalates contents were below 200mg 100[-1]g in five examined plants with the exception of Chenopodium album [413mg 100[-1]g]. Antioxidant activity of Caralluma edulis was found maximum while the rest of the examined plants had moderate levels

4.
Pakistan Journal of Pharmaceutical Sciences. 2015; 28 (5): 1699-1704
in English | IMEMR | ID: emr-166663

ABSTRACT

The present study evaluates the phytochemical screenings, antioxidant activity and antimicrobial assay of Apium graveolens L. The phytochemical screening showed the presence of flavonoids, tannins, saponins and steroids in Apium graveolens while terpenoids was absent. The total phenolic content was slightly higher in methanolic fraction [63.46 +/- 12.00mg GAE/g] followed by ethanol [36.60 +/- 12.28 mg GAE/g] and hexane fractions [34.86 +/- 6.96mg GAE/g]. The flavonoid content was high in methanolic extract [56.95 +/- 7.14mg Quorcetin/g] and low level of the content was found in methylated spirit extract [29.2 +/- 3.15mg Quercitin/g]. Antioxidant activity assayed by FRAP was higher in methanolic fraction [12.48 +/- 1.06 mmole of FeSO[4] equivalent/litre of extract] compared with other extracts. Likewise, good antimicrobial activity was measured by crude ethanol fraction against S. aureus [MIC=0.12 +/- 0.03microg/ml] and S. typhi [MIC= 0.5 +/- 0.2microg/ml]. Results also that ethanolic fraction was effective against A. flavus [MIC= 05 +/- 1.0microg/ml]


Subject(s)
Phytochemicals , In Vitro Techniques , Antioxidants , Plant Extracts , Plants, Medicinal , Anti-Infective Agents
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